Process Scaleup: Volume 2-Focus on Equipment - electronic book

Safe, cost-effective scaleup is an essential aspect of moving promising laboratory developments to full-scale commercial production. This PDF contains practical, how-to engineering articles focused on equipment-related aspects encountered during scaleup efforts, pilot-plant design, and operational safety.

Articles provide guidance on preparing proper design bases, exploiting chemical physical properties, managing heat and mass transfer challenges, addressing mixing issues, and reconciling piping and safety considerations. Emphasis is placed on preventing runaway reactions and ensuring incident-free pilot-plant operation.

Features & Benefits

• Guidance on safe and cost-effective scaleup from lab to pilot and full-scale operations
• Practical tips on pilot-plant design, operation, and safety considerations
• Insights on managing heat and mass transfer, mixing, and exothermic reactions
• Strategies for minimizing risks related to piping, instrumentation, and equipment
• Cost-estimating techniques for pilot-plant projects, including contingency planning
• Focus on incident-free scaleup and preventing fires, explosions, and runaway reactions

Audience

• Process and chemical engineers
• Pilot plant and scaleup engineers
• Project engineers in process development
• Plant operations and safety professionals
• Technical consultants and researchers in CPI

Articles Include

• A Checklist for Safer Chemical Batch Reactions
• Designing Safer Process Plants
• Focus on Physical Properties To Improve Processes
• Safe Scaleup of Exothermic Reactions
• Principles of P&ID Development
• Ten Things You May Not Know About Liquid Mixing Scaleup
• Millichannel Reactors: A Practical Middle Ground for Production
• Calculations in Process Engineering
• Pilot Plant Cost Estimating: Make Intelligent Use of Contingency
• Adiabatic-Temperature Rise: An Awkward Calculation Made Simple
• Active Management of Pipespool Fabricators
• Design Safety Instrumented Systems with Relevant Data
• How to Prepare a Process Design Basis
• Short-Cut Piping Costs
• Mass Transfer in Fermentation Scaleup
• Preventing Fires and Explosions in Pilot Plants
• Avoiding Runaway Reactions
• Runaway Reactions: Ignore the Chemistry At Your Peril
• “But What Will It Cost?” The Keys to Success in Pilot Plant Cost Estimating
• Piping: Minimizing the Risk of ‘Pre-buys’
• Heat Transfer for Huge-Scale Fermentation
• Strategies for Water Reuse